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Description

Spine 25 , 30053013 (2000)

In preclinical research, this mechanism has been associated with selective apoptosis of senescent cells while preserving healthy cellular populations

Next, Cys63 nucleophilically attacks the sulfide of Cys58, releasing a GS-anion, which, in turn, picks up a solvent proton and is released from the enzyme, thereby creating the second GSH